Emergency Line (+30) 6944-332090
HealthFlex
×
  • Home
  • The Doctor
  • Services
    • Well child visits
    • General Pediatrics
    • Allergies
      • Atopic dermatitis
      • Food allergies
      • Drug allergy
      • Anaphylaxis
  • News
    • Media
  • FAQ
  • Contact
  • English
  • Greek

Νέα από το χώρο της Ατοπικής Δερματίτιδας

Νέα από το χώρο της Ατοπικής Δερματίτιδας

Treatment of Staphylococcus aureus colonization in atopic dermatitis decreases disease severity.
Huang JT1, Abrams M, Tlougan B, Rademaker A, Paller AS.
Author information
Abstract

OBJECTIVES:

The goals were to determine the prevalence of community-acquired methicillin-resistant Staphylococcus aureus colonization in patients with atopic dermatitis and to determine whether suppression of S aureus growth with sodium hypochlorite (bleach) baths and intranasal mupirocin treatment improves eczema severity.

METHODS:

A randomized, investigator-blinded, placebo-controlled study was conducted with 31 patients, 6 months to 17 years of age, with moderate to severe atopic dermatitis and clinical signs of secondary bacterial infections. All patients received orally administered cephalexin for 14 days and were assigned randomly to receive intranasal mupirocin ointment treatment and sodium hypochlorite (bleach) baths (treatment arm) or intranasal petrolatum ointment treatment and plain water baths (placebo arm) for 3 months. The primary outcome measure was the Eczema Area and Severity Index score.

RESULTS:

The prevalence of community-acquired methicillin-resistant S aureus in our study (7.4% of our S aureus-positive skin cultures and 4% of our S aureus-positive nasal cultures) was much lower than that in the general population with cultures at Children’s Memorial Hospital (75%-85%). Patients in the group that received both the dilute bleach baths and intranasal mupirocin treatment showed significantly greater mean reductions from baseline in Eczema Area and Severity Index scores, compared with the placebo group, at the 1-month and 3-month visits. The mean Eczema Area and Severity Index scores for the head and neck did not decrease for patients in the treatment group, whereas scores for other body sites (submerged in the dilute bleach baths) decreased at 1 and 3 months, in comparison with placebo-treated patients.

CONCLUSIONS:

Chronic use of dilute bleach baths with intermittent intranasal application of mupirocin ointment decreased the clinical severity of atopic dermatitis in patients with clinical signs of secondary bacterial infections. Patients with atopic dermatitis do not seem to have increased susceptibility to infection or colonization with resistant strains of S aureus.

Search

News & Articles

  • FPIES ή σύνδρομο εντεροκολίτιδας επαγόμενης από τροφική πρωτεΐνη

    Της Μαρίας Κουλούρη MD,PhD Παιδιάτρου Παιδοαλλεργιολόγου Η αλλεργία στις τροφές...

  • Stress και εξανθήματα στα παιδιά

    Τα εξανθήματα είναι συνηθισμένο πρόβλημα στην παιδική ηλικία. Ανάλογα με...

  • Ατοπική Δερματίτιδα

    ΤΙ ΕΙΝΑΙ Η ΑΤΟΠΙΚΗ ΔΕΡΜΑΤΙΤΙΔΑ; Η ατοπική δερματίτιδα είναι μια...

  • Αλλεργίες του φθινοπώρου στα παιδιά

    ΞΕΧΩΡΙΖΟΥΜΕ ΤΗΝ ΙΩΣΗ ΑΠΟ ΤΗΝ ΑΛΛΕΡΓΙΑ ΚΑΙ ΤΗΝ ΑΝΤΙΜΕΤΩΠΙΖΟΥΜΕ ΑΝΑΛΟΓΑ...

  • Ιατρικές Οδηγίες για καλές διακοπές

    Αγαπητοί γονείς Οι διακοπές πλησιάζουν και είναι πολύ σημαντικό να...

Request Appointment

    Your Name (required)

    Your Email (required)

    Reason for visit

    Your Message

    Dr Maria Koulouri MD, PhD, Pediatrician- Pediatric Allergist: High quality pediatric medical service and Allergy consultation from the very first moment of life until adolescence.

    (+30) 210 6121145

    info@paidi-allergia.gr

    11 Irinis Leof., Pefki, B.O. 15121

    MENU

    • The Doctor
    • Services
      • Well child visits
      • General Pediatrics
      • Allergies
    • General Pediatrics
    • News
    • Contact
    • Terms of use
    • Privacy policy

    Latest Articles

    • FPIES ή σύνδρομο εντεροκολίτιδας επαγόμενης από τροφική πρωτεΐνη
    • Stress και εξανθήματα στα παιδιά
    • Ατοπική Δερματίτιδα
    • Αλλεργίες του φθινοπώρου στα παιδιά
    Copyright & copy;2019 all rights reserved "paidi-allergia.gr "
    Designed by WEBMAZE